CNTNAP1 Antikörper

Produktnummer ABIN7227990

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CNTNAP1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für CNTNAP1 Antikörper (ABIN7227990)

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNTNAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CNTNAP1 Antikörper

Verwendungszweck: Rabbit Anti-CNTP1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CNTP1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CNTP1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CNTNAP1

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Andere Bezeichnung: CNTP1

Hintergrund: Contactin-associated protein 1, Caspr, Caspr1, Neurexin IV, Neurexin-4, p190CNTNAP1 product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for contactin-associated protein, includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Molekulargewicht: 152kD

Gen-ID: 8506

UniProt: P78357

Pathways: Cell-Cell Junction Organization