C8B Antikörper (AA 371-420)

Produktnummer ABIN7226914

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch C8B in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für C8B Antikörper (AA 371-420) (ABIN7226914)

Target: C8B (Complement Component 8, beta Polypeptide (C8B))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C8B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-C8B Antikörper

Bindungsspezifität: AA 371-420

Verwendungszweck: C8 β Polyclonal Antibody

Spezifität: C8 β Polyclonal Antibody detects endogenous levels of C8 β.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from C8 beta at AA range: 371-420

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu C8B

Target: C8B (Complement Component 8, beta Polypeptide (C8B))

Andere Bezeichnung: C8 beta

Hintergrund: Rabbit Anti-C8 β Polyclonal Antibody,Complement component C8 beta chain, Complement component 8 subunit beta,C8B (complement C8 beta chain) encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.,C8 β

Molekulargewicht: observerd band 70kDa

Gen-ID: 732

UniProt: P07358

Pathways: Komplementsystem