CHD1L Antikörper (Internal Region)

Produktnummer ABIN7217606

Der Kaninchen-Polyklonal Anti-CHD1L-Antikörper wurde für WB und ELISA validiert. Er ist geeignet zum Nachweis von CHD1L in Proben aus Human und Maus. }

Kurzübersicht für CHD1L Antikörper (Internal Region) (ABIN7217606)

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHD1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CHD1L Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: CHD1L Polyclonal Antibody

Spezifität: CHD1L Polyclonal Antibody detects endogenous levels of CHD1L protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CHD1L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CHD1L

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Andere Bezeichnung: CHD1L

Hintergrund: Rabbit Anti-CHD1L Polyclonal Antibody,CHD1L, ALC1, Chromodomain-helicase-DNA-binding protein 1-like, Amplified in liver cancer protein 1,CHD1L encodes a DNA helicase protein involved in DNA repair. The chromodomain-helicase-DNA-binding protein 1-like converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like) is a Protein Coding gene. Diseases associated with CHD1L include fibrosarcoma of bone. Among its related pathways are Chromatin Regulation / Acetylation and DNA Double-Strand Break Repair. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.,Chromodomain-helicase-DNA-binding protein 1-like

Molekulargewicht: observerd band 101kDa

Gen-ID: 9557

UniProt: Q86WJ1