CHRNA10 Antikörper (AA 370-450)

Produktnummer ABIN7213448

Der Kaninchen Polyklonal anti-CHRNA10 Antikörper (ABIN7213448) detektiert spezifisch CHRNA10 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für CHRNA10 Antikörper (AA 370-450) (ABIN7213448)

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CHRNA10 Antikörper

Bindungsspezifität: AA 370-450

Verwendungszweck: AChRα10 Polyclonal Antibody

Spezifität: AChRα10 Polyclonal Antibody detects endogenous levels of AChRα10 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human AChRalpha10 at AA range: 370-450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CHRNA10

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Andere Bezeichnung: AChRalpha10

Hintergrund: Rabbit Anti-AChRα10 Polyclonal Antibody,CHRNA10, NACHRA10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10,Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα10, also known as CHRNA10, is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes. AChRα10 forms a hetero-oligomeric channels in conjunction with AChRα9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli.,Neuronal acetylcholine receptor subunit alpha-10

Gen-ID: 57053

UniProt: Q9GZZ6

Pathways: Sensory Perception of Sound, Synaptic Membrane