CHRNA10 Antikörper (AA 25-240)

Produktnummer ABIN3017240

Produktdetails anti-CHRNA10 Antikörper

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Bindungsspezifität: AA 25-240

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AEGRLALKLF RDLFANYTSA LRPVADTDQT LNVTLEVTLS QIIDMDERNQ VLTLYLWIRQ EWTDAYLRWD PNAYGGLDAI RIPSSLVWRP DIVLYNKADA QPPGSASTNV VLRHDGAVRW DAPAITRSSC RVDVAAFPFD AQHCGLTFGS WTHGGHQLDV RPRGAAASLA DFVENVEWRV LGMPARRRVL TYGCCSEPYP DVTFTLLLRR RAAAYV

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CHRNA10 (NP_065135.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CHRNA10

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Andere Bezeichnung: CHRNA10 (CHRNA10 Produkte)

Synonyme: si:dkey-24p1.3 antikoerper, ALPHA 10 nAChR antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 10 antikoerper, cholinergic receptor nicotinic alpha 10 subunit antikoerper, cholinergic receptor, nicotinic, alpha 10a antikoerper, neuronal acetylcholine receptor subunit alpha-10 antikoerper, cholinergic receptor, nicotinic, alpha 10 (neuronal) antikoerper, Chrna10 antikoerper, CHRNA10 antikoerper, chrna10a antikoerper, LOC100344381 antikoerper

Hintergrund: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.,CHRNA10,Signal Transduction,Neuroscience,Calcium Signaling,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNA10

Molekulargewicht: 49 kDa

Gen-ID: 57053

UniProt: Q9GZZ6

Pathways: Sensory Perception of Sound, Synaptic Membrane