CEP290 Antikörper (AA 740-820)

Produktnummer ABIN7214146

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CEP290 in ELISA und WB. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CEP290 Antikörper (AA 740-820) (ABIN7214146)

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP290 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-CEP290 Antikörper

Bindungsspezifität: AA 740-820

Verwendungszweck: CEP290 Polyclonal Antibody

Spezifität: CEP290 Polyclonal Antibody detects endogenous levels of CEP290 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CEP290 at AA range: 740-820

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CEP290

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Andere Bezeichnung: CEP290

Hintergrund: Rabbit Anti-CEP290 Polyclonal Antibody,CEP290, BBS14, KIAA0373, NPHP6, Centrosomal protein of 290 kDa, Cep290, Bardet-Biedl syndrome 14 protein, Cancer/testis antigen 87, CT87, Nephrocystin-6, Tumor antigen se2-2,CEP290 encodes a protein (centrosomal protein 290) with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in CEP290 have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.,Centrosomal protein of 290 kDa

Molekulargewicht: observerd band 290kDa

Gen-ID: 80184

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase