CENPF Antikörper (AA 2190-2270)

Produktnummer ABIN7227826

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CENPF in IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CENPF Antikörper (AA 2190-2270) (ABIN7227826)

Target: CENPF (Centromere Protein F (CENPF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPF Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CENPF Antikörper

Bindungsspezifität: AA 2190-2270

Verwendungszweck: Rabbit Anti-CENPF Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CENPF protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CENPF protein at AA range: 2190-2270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CENPF

Target: CENPF (Centromere Protein F (CENPF))

Andere Bezeichnung: CENPF

Hintergrund: Centromere protein F, CENP-F, AH antigen, Kinetochore protein CENPF, MitosinCENPF (Centromere Protein F) encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

Molekulargewicht: 353kD

Gen-ID: 1063

UniProt: P49454

Pathways: Chromatin Binding, M Phase, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion