CENPF Antikörper (AA 2190-2270)

Produktnummer ABIN7227826

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CENPF in IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CENPF Antikörper (AA 2190-2270) (ABIN7227826)

Target: CENPF (Centromere Protein F (CENPF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPF Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CENPF Antikörper

Bindungsspezifität: AA 2190-2270

Verwendungszweck: CENPF Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CENPF protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CENPF protein at AA range: 2190-2270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CENPF

Target: CENPF (Centromere Protein F (CENPF))

Andere Bezeichnung: CENPF

Hintergrund: Rabbit Anti-CENPF Polyclonal Antibody,Centromere protein F, CENP-F, AH antigen, Kinetochore protein CENPF, Mitosin,CENPF (Centromere Protein F) encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.,CENPF

Molekulargewicht: observerd band 353kDa

Gen-ID: 1063

UniProt: P49454

Pathways: Chromatin Binding, M Phase, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion