CENPA Antikörper (pSer7)

Produktnummer ABIN7219060

Der Kaninchen Polyklonal anti-CENPA Antikörper (ABIN7219060) detektiert spezifisch CENPA in ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CENPA Antikörper (pSer7) (ABIN7219060)

Target: CENPA (Centromere Protein A (CENPA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPA Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-CENPA Antikörper

Bindungsspezifität: pSer7

Verwendungszweck: Rabbit Anti-CENP-A (phospho Ser7) Polyclonal Antibody

Spezifität: Phospho-CENP-A (S7) Polyclonal Antibody detects endogenous levels of CENP-A protein only when phosphorylated at S7.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CENP-A Phospho-Ser7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CENPA

Target: CENPA (Centromere Protein A (CENPA))

Andere Bezeichnung: CENP-A

Hintergrund: CENPA, Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-ACentromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gen-ID: 1058

UniProt: P49450

Pathways: Chromatin Binding, Maintenance of Protein Location