CIDEB Antikörper (AA 60-140)

Produktnummer ABIN7214210

Dieser Anti-CIDEB Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CIDEB in ELISA, WB, IF und IHC (p). Geeignet für Human und Maus.

Kurzübersicht für CIDEB Antikörper (AA 60-140) (ABIN7214210)

Target: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIDEB Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CIDEB Antikörper

Bindungsspezifität: AA 60-140

Verwendungszweck: CIDE-B Polyclonal Antibody

Spezifität: CIDE-B Polyclonal Antibody detects endogenous levels of CIDE-B protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CIDE-B at AA range: 60-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CIDEB

Target: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Andere Bezeichnung: CIDE-B

Hintergrund: Rabbit Anti-CIDE-B Polyclonal Antibody,CIDEB, Cell death activator CIDE-B, Cell death-inducing DFFA-like effector B,Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes and bone marrow.,Cell death activator CIDE-B

Molekulargewicht: observerd band 24kDa

Gen-ID: 27141

UniProt: Q9UHD4