CIDEB Antikörper (C-Term)

Produktnummer ABIN499631

Der Kaninchen Polyklonal anti-CIDEB Antikörper wird verwendet zum Nachweis von CIDEB in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für CIDEB Antikörper (C-Term) (ABIN499631)

Target: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIDEB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CIDEB Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to CIDE-B.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: CIDE-B antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human CIDE-B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CIDE-B antibody can be used for detection of CIDE-B at 0.5 - 1 μg/mLImmunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CIDEB

Target: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Andere Bezeichnung: CIDE-B

Hintergrund: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (1,2). Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes and bone marrow. CIDE-B antibody has no cross activity to CIDE-A.Synonyms: CIDE B, CIDEB, Cell Death Activator CIDE-B, Cell Death-Inducing DFFA-Like Effector B

Gen-ID: 27141

UniProt: Q9UHD4