CDC42EP5 Antikörper (AA 1-80)

Produktnummer ABIN7214112

Der Kaninchen Polyklonal Anti-CDC42EP5 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, CDC42EP5 in Proben von Human und Maus zu detektieren.

Kurzübersicht für CDC42EP5 Antikörper (AA 1-80) (ABIN7214112)

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC42EP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CDC42EP5 Antikörper

Bindungsspezifität: AA 1-80

Verwendungszweck: Cdc42EP5 Polyclonal Antibody

Spezifität: Cdc42EP5 Polyclonal Antibody detects endogenous levels of Cdc42EP5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Cdc42EP5 at AA range: 1-80

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CDC42EP5

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Andere Bezeichnung: Cdc42EP5

Hintergrund: Rabbit Anti-Cdc42EP5 Polyclonal Antibody,CDC42EP5, BORG3, CEP5, Cdc42 effector protein 5, Binder of Rho GTPases 3,Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts.,Cdc42 effector protein 5

Molekulargewicht: observerd band 22kDa

Gen-ID: 148170

UniProt: Q6NZY7

Pathways: Regulation of Actin Filament Polymerization