CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2785099, Anbieter: Anmelden zum Anzeigen
Antigen
  • Borg3
  • CEP5
  • 1700027J19Rik
  • 2010007O02Rik
  • C85526
  • CDC42 effector protein 5
  • CDC42 effector protein (Rho GTPase binding) 5
  • CDC42EP5
  • Cdc42ep5
Epitop
Middle Region
8
2
1
Reaktivität
Rind (Kuh), Hund, Human, Maus, Ratte (Rattus)
20
12
1
1
1
Wirt
Kaninchen
20
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
18
12
3
3
2
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CDC42EP5
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN974736.
Sequenz HVGRGGDAFG DTSFLSRHGG GPPPEPRAPP AGAPRSPPPP AVPQSAAPSP
Homologie Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against CDC42EP5. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Antigen
Andere Bezeichnung CDC42EP5 (CDC42EP5 Antibody Abstract)
Hintergrund CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.
Alias Symbols: Borg3, CEP5, MGC21945, MGC71153
Protein Interaction Partner: SEPT7, CDC42, Sept6, Sept2,
Protein Size: 148
Molekulargewicht 15 kDa
Gen-ID 148170
NCBI Accession NM_145057, NP_659494
UniProt Q6NZY7
Pathways Regulation of Actin Filament Polymerization
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 148 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5) (Middle Region) antibody (ABIN2785099) WB Suggested Anti-CDC42EP5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Allgemeine Veröffentlichungen Joberty, Perlungher, Sheffield, Kinoshita, Noda, Haystead, Macara: "Borg proteins control septin organization and are negatively regulated by Cdc42." in: Nature cell biology, Vol. 3, Issue 10, pp. 861-6, 2001 (PubMed).

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