CLK2 Antikörper (AA 1-80)

Produktnummer ABIN7214246

Der Kaninchen Polyklonal Anti-CLK2 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, CLK2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CLK2 Antikörper (AA 1-80) (ABIN7214246)

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CLK2 Antikörper

Bindungsspezifität: AA 1-80

Verwendungszweck: CLK2 Polyclonal Antibody

Spezifität: CLK2 Polyclonal Antibody detects endogenous levels of CLK2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human CLK2 at AA range: 1-80

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CLK2

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Andere Bezeichnung: CLK2

Hintergrund: Rabbit Anti-CLK2 Polyclonal Antibody,CLK2, Dual specificity protein kinase CLK2, CDC-like kinase 2,CLK2 encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that CLK2 is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for CLK2 on chromosome 7. Alternative splicing results in multiple transcript variants.,Dual specificity protein kinase CLK2

Molekulargewicht: observerd band 60kDa

Gen-ID: 1196

UniProt: P49760

Pathways: Regulation of Carbohydrate Metabolic Process