CD70 Antikörper (AA 150-193)

Produktnummer ABIN7227764

Der Kaninchen Polyklonal anti-CD70 Antikörper wird verwendet zum Nachweis von CD70 in Proben von Human und Maus. Er wurde validiert für ELISA und IHC (p).

Kurzübersicht für CD70 Antikörper (AA 150-193) (ABIN7227764)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CD70 Antikörper

Bindungsspezifität: AA 150-193

Verwendungszweck: CD70 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CD70

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CD70 protein at AA range: 150-193

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund: Rabbit Anti-CD70 Polyclonal Antibody,CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD antigen CD70,The protein encoded by CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Akt Signaling. is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Akt Signaling.,CD70

Gen-ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints