Cathepsin G Antikörper (Cleaved-Ile21)

Produktnummer ABIN7212462

Der Kaninchen Polyklonal Anti-Cathepsin G Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Cathepsin G in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Cathepsin G Antikörper (Cleaved-Ile21) (ABIN7212462)

Target: Cathepsin G (CTSG)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin G Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Cathepsin G Antikörper

Bindungsspezifität: AA 10-90, Cleaved-Ile21

Verwendungszweck: Cleaved-Cathepsin G (I21) Polyclonal Antibody

Spezifität: Cleaved-Cathepsin G (I21) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin G protein resulting from cleavage adjacent to I21.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Cathepsin G at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Cathepsin G

Target: Cathepsin G (CTSG)

Andere Bezeichnung: Cathepsin G

Hintergrund: Rabbit Anti-Cleaved-Cathepsin G (I21) Polyclonal Antibody,CTSG, Cathepsin G, CG,The protein encoded by CTSG, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease (cathepsin G) has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, cathepsin G is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this CTSG.,Cathepsin G

Molekulargewicht: observerd band 29+36kDa

Gen-ID: 1511

UniProt: P08311

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones