Cathepsin D Antikörper (Cleaved-Leu169)

Produktnummer ABIN7212452

Der Kaninchen Polyklonal Anti-Cathepsin D Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Cathepsin D in Proben von Human zu detektieren.

Kurzübersicht für Cathepsin D Antikörper (Cleaved-Leu169) (ABIN7212452)

Target: Cathepsin D (CTSD)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Cathepsin D Antikörper

Bindungsspezifität: AA 120-200, Cleaved-Leu169

Verwendungszweck: Cleaved-Cathepsin D HC (L169) Polyclonal Antibody

Spezifität: Cleaved-Cathepsin D HC (L169) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin D HC protein resulting from cleavage adjacent to L169.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Cathepsin D HC at AA range: 120-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Cathepsin D

Target: Cathepsin D (CTSD)

Andere Bezeichnung: Cathepsin D HC

Hintergrund: Rabbit Anti-Cleaved-Cathepsin D HC (L169) Polyclonal Antibody,CTSD, CPSD, Cathepsin D,CTSD encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in CTSD play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.,Cathepsin D

Molekulargewicht: observerd band 27kDa

Gen-ID: 1509

UniProt: P07339

Pathways: Peptide Hormone Metabolism