Caspase 1 p20 Antikörper (Cleaved-Asn120)

Produktnummer ABIN7225262

Der Kaninchen Polyklonal Anti-Caspase 1 p20 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Caspase 1 p20 in Proben von Human zu detektieren.

Kurzübersicht für Caspase 1 p20 Antikörper (Cleaved-Asn120) (ABIN7225262)

Target: Caspase 1 p20

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 1 p20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Caspase 1 p20 Antikörper

Bindungsspezifität: AA 70-150, Cleaved-Asn120

Verwendungszweck: Cleaved-Caspase-1 p20 (N120) Polyclonal Antibody

Spezifität: Cleaved-Caspase-1 p20 (N120) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-1 p20 protein resulting from cleavage adjacent to N120.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Caspase-1 p20 at AA range: 70-150

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Caspase 1 p20

Target: Caspase 1 p20

Andere Bezeichnung: Caspase-1 p20

Hintergrund: Rabbit Anti-Cleaved-Caspase-1 p20 (N120) Polyclonal Antibody,CASP1, IL1BC, IL1BCE, Caspase-1, CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45,CASP1 (caspase 1) encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP1 was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. CASP1 has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.,Caspase-1

Molekulargewicht: observerd band 18kDa

Gen-ID: 834

UniProt: P29466