Cardiotrophin 1 Antikörper (AA 151-200)

Produktnummer ABIN7227598

Der Kaninchen Polyklonal anti-Cardiotrophin 1 Antikörper wird verwendet zum Nachweis von Cardiotrophin 1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Cardiotrophin 1 Antikörper (AA 151-200) (ABIN7227598)

Target: Cardiotrophin 1 (CTF1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cardiotrophin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Cardiotrophin 1 Antikörper

Bindungsspezifität: AA 151-200

Verwendungszweck: Rabbit Anti-Cardiotrophin-1 Polyclonal Antibody

Spezifität: This antibody detects endogenous levels of Cardiotrophin-1

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Cardiotrophin-1 protein at AA range: 151-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cardiotrophin 1

Target: Cardiotrophin 1 (CTF1)

Andere Bezeichnung: Cardiotrophin-1

Hintergrund: Cardiotrophin-1, CT-1CTF1 (Cardiotrophin 1) is a Protein Coding gene. Diseases associated with CTF1 include Neonatal Stroke and Hypertensive Heart Disease. Among its related pathways are Jak-STAT signaling pathway (KEGG) and NFAT and Cardiac Hypertrophy. The protein encoded by CTF1 is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for CTF1.

Molekulargewicht: 23kD

Gen-ID: 1489

UniProt: Q16619

Pathways: JAK-STAT Signalweg