CPE Antikörper (C-Term)

Produktnummer ABIN7217878

Dieser Anti-CPE Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CPE in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für CPE Antikörper (C-Term) (ABIN7217878)

Target: CPE (Carboxypeptidase E (CPE))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CPE Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CPE Polyclonal Antibody

Spezifität: CPE Polyclonal Antibody detects endogenous levels of CPE protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human CPE

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CPE

Target: CPE (Carboxypeptidase E (CPE))

Andere Bezeichnung: CPE

Hintergrund: Rabbit Anti-CPE Polyclonal Antibody,CPE, Carboxypeptidase E, CPE, Carboxypeptidase H, CPH, Enkephalin convertase, Prohormone-processing carboxypeptidase,CPE encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes.,Carboxypeptidase E

Molekulargewicht: observerd band 53kDa

Gen-ID: 1363

UniProt: P16870

Pathways: Peptide Hormone Metabolism, Synaptic Membrane