C1R Antikörper (Cleaved-Arg463)

Produktnummer ABIN7224738

Der Kaninchen Polyklonal anti-C1R Antikörper (ABIN7224738) detektiert spezifisch C1R in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für C1R Antikörper (Cleaved-Arg463) (ABIN7224738)

Target: C1R (Complement Component 1, R Subcomponent (C1R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-C1R Antikörper

Bindungsspezifität: AA 390-470, Cleaved-Arg463

Verwendungszweck: Rabbit Anti-Cleaved-C1r HC (R463) Polyclonal Antibody

Spezifität: Cleaved-C1r HC (R463) Polyclonal Antibody detects endogenous levels of fragment of activated C1r HC protein resulting from cleavage adjacent to R463.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human C1r HC at AA range: 390-470

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu C1R

Target: C1R (Complement Component 1, R Subcomponent (C1R))

Andere Bezeichnung: C1r HC

Hintergrund: C1R, Complement C1r subcomponent, Complement component 1 subcomponent rThe first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This antibody recognizes full-length C1r chain and the cleaved B chain.

Molekulargewicht: 51kD

Gen-ID: 715

UniProt: P00736

Pathways: Komplementsystem