BMX Antikörper
Kurzübersicht für BMX Antikörper (ABIN7213832)
Target
Alle BMX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- Rabbit Anti-Bmx Polyclonal Antibody
-
Spezifität
- Bmx Polyclonal Antibody detects endogenous levels of Bmx protein.
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- Synthesized peptide derived from human Bmx around the non-phosphorylation site of Y566
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
Haltbarkeit
- 12 months
-
-
- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
-
Andere Bezeichnung
- Bmx
-
Hintergrund
- BMX, Cytoplasmic tyrosine-protein kinase BMX, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase, ETK, NTK38BMX encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein (BMX non-receptor tyrosine kinase)contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for BMX.
-
Molekulargewicht
- 78kD
-
Gen-ID
- 660
-
UniProt
- P51813
Target
-