BLM Antikörper (pThr99)

Produktnummer ABIN7224218

Der Kaninchen Polyklonal anti-BLM Antikörper wird verwendet zum Nachweis von BLM in Proben von Human. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für BLM Antikörper (pThr99) (ABIN7224218)

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BLM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BLM Antikörper

Bindungsspezifität: pThr99

Verwendungszweck: BLM (phospho Thr99) Polyclonal Antibody

Spezifität: Phospho-BLM (T99) Polyclonal Antibody detects endogenous levels of BLM protein only when phosphorylated at T99.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human BLM Phospho-Thr99

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu BLM

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Andere Bezeichnung: BLM

Hintergrund: Rabbit Anti-BLM (phospho Thr99) Polyclonal Antibody,BLM, RECQ2, RECQL3, Bloom syndrome protein, DNA helicase, RecQ-like type 2, RecQ2, RecQ protein-like 3,The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.,Bloom syndrome protein

Molekulargewicht: observerd band 159kDa

Gen-ID: 641

UniProt: P54132

Pathways: DNA Reparatur