Beclin 1 Antikörper (AA 110-190)

Produktnummer ABIN7226846

Der Kaninchen Polyklonal anti-Beclin 1 Antikörper (ABIN7226846) detektiert spezifisch Beclin 1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Huhn.

Kurzübersicht für Beclin 1 Antikörper (AA 110-190) (ABIN7226846)

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reaktivität: Human, Maus, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Beclin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Beclin 1 Antikörper

Bindungsspezifität: AA 110-190

Verwendungszweck: Rabbit Anti-Beclin-1 Polyclonal Antibody

Spezifität: Beclin-1 Polyclonal Antibody detects endogenous levels of Beclin-1.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Beclin-1 at AA range: 110-190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Beclin 1

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Andere Bezeichnung: Beclin-1

Hintergrund: Beclin 1, autophagy relatedBECN1 (beclin 1) encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 55kD

Gen-ID: 8678

UniProt: Q14457

Pathways: Autophagie