BCL2L12 Antikörper (AA 60-140)

Produktnummer ABIN7225300

Der Kaninchen Polyklonal anti-BCL2L12 Antikörper wird verwendet zum Nachweis von BCL2L12 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für BCL2L12 Antikörper (AA 60-140) (ABIN7225300)

Target: BCL2L12 (BCL2-Like 12 (Proline Rich) (BCL2L12))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL2L12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-BCL2L12 Antikörper

Bindungsspezifität: AA 60-140

Verwendungszweck: Rabbit Anti-BCL2L12 Polyclonal Antibody

Spezifität: BCL2L12 Polyclonal Antibody detects endogenous levels of BCL2L12 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human BCL2L12 at AA range: 60-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu BCL2L12

Target: BCL2L12 (BCL2-Like 12 (Proline Rich) (BCL2L12))

Andere Bezeichnung: BCL2L12

Hintergrund: BCL2L12, BPR, Bcl-2-like protein 12, Bcl2-L-12, Bcl-2-related proline-rich proteinBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome 3. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 34kD

Gen-ID: 83596

UniProt: Q9HB09