BIK Antikörper (pSer35)

Produktnummer ABIN7224186

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch BIK in ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BIK Antikörper (pSer35) (ABIN7224186)

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIK Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BIK Antikörper

Bindungsspezifität: pSer35

Verwendungszweck: NBK (phospho Ser35) Polyclonal Antibody

Spezifität: Phospho-NBK (S35) Polyclonal Antibody detects endogenous levels of NBK protein only when phosphorylated at S35.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human NBK Phospho-Ser35

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu BIK

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Andere Bezeichnung: NBK

Hintergrund: Rabbit Anti-NBK (phospho Ser35) Polyclonal Antibody,BIK, NBK, Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4,The protein encoded by BIK (BCL2 interacting killer) shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.,Bcl-2-interacting killer

Gen-ID: 638

UniProt: Q13323

Pathways: Positive Regulation of Endopeptidase Activity