Der Kaninchen Polyklonal anti-ATG10 Antikörper wird verwendet zum Nachweis von ATG10 in Proben von Human und Maus. Er wurde validiert für ELISA, IHC und IF.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
ATG10
(Autophagy Related 10 (ATG10))
Andere Bezeichnung
ATG10
Hintergrund
Ubiquitin-like-conjugating enzyme ATG10, Autophagy-related protein 10, APG10-likeAutophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: aTG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A, MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al. 2003 ATG10 (Autophagy Related 10) is a Protein Coding gene. Diseases associated with ATG10 include Anthracosis. Among its related pathways are Cellular Senescence (REACTOME) and Autophagy Pathway.