AATK Antikörper (AA 1110-1190)

Produktnummer ABIN7229418

Der Kaninchen Polyklonal anti-AATK Antikörper (ABIN7229418) detektiert spezifisch AATK in ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für AATK Antikörper (AA 1110-1190) (ABIN7229418)

Target: AATK (Apoptosis-Associated tyrosine Kinase (AATK))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AATK Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-AATK Antikörper

Bindungsspezifität: AA 1110-1190

Verwendungszweck: Rabbit Anti-LMTK1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of LMTK1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LMTK1 protein at AA range: 1110-1190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu AATK

Target: AATK (Apoptosis-Associated tyrosine Kinase (AATK))

Andere Bezeichnung: LMTK1

Hintergrund: Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BPThe protein encoded by AATK contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of AATK may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. AATK has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for AATK.

Molekulargewicht: 151kD

Gen-ID: 9625

UniProt: Q6ZMQ8

Pathways: RTK Signalweg, Regulation of Cell Size