AMH Antikörper (AA 380-460)

Produktnummer ABIN7229680

Dieser Anti-AMH Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von AMH in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für AMH Antikörper (AA 380-460) (ABIN7229680)

Target: AMH (Anti-Mullerian Hormone (AMH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-AMH Antikörper

Bindungsspezifität: AA 380-460

Verwendungszweck: MIS Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MIS protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MIS protein at AA range: 380-460

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu AMH

Target: AMH (Anti-Mullerian Hormone (AMH))

Andere Bezeichnung: MIS

Hintergrund: Rabbit Anti-MIS Polyclonal Antibody,Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS,AMH encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.,MIS

Molekulargewicht: observerd band 61kDa

Gen-ID: 268

UniProt: P03971

Pathways: Negative Regulation of Hormone Secretion