APLP2 Antikörper (AA 210-290)

Produktnummer ABIN7213628

Der Kaninchen Polyklonal Anti-APLP2 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, APLP2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für APLP2 Antikörper (AA 210-290) (ABIN7213628)

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APLP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-APLP2 Antikörper

Bindungsspezifität: AA 210-290

Verwendungszweck: APLP-2 Polyclonal Antibody

Spezifität: APLP-2 Polyclonal Antibody detects endogenous levels of APLP-2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human APLP-2 at AA range: 210-290

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Andere Bezeichnung: APLP-2

Hintergrund: Rabbit Anti-APLP-2 Polyclonal Antibody,APLP2, APPL2, Amyloid-like protein 2, APLP-2, APPH, Amyloid protein homolog, CDEI box-binding protein, CDEBP,APLP2 encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,Amyloid-like protein 2

Gen-ID: 334

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour