ATF6B Antikörper (AA 370-450)

Produktnummer ABIN7213716

Dieser Anti-ATF6B Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ATF6B in WB, ELISA und IHC (p). Geeignet für Human.

Kurzübersicht für ATF6B Antikörper (AA 370-450) (ABIN7213716)

Target: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATF6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ATF6B Antikörper

Bindungsspezifität: AA 370-450

Verwendungszweck: ATF-6β Polyclonal Antibody

Spezifität: ATF-6β Polyclonal Antibody detects endogenous levels of ATF-6β protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human ATF-6beta at AA range: 370-450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ATF6B

Target: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Andere Bezeichnung: ATF-6beta

Hintergrund: Rabbit Anti-ATF-6β Polyclonal Antibody,ATF6B, CREBL1, G13, Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein,The protein (activating transcription factor 6 beta) encoded by ATF6B is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for ATF6B.,Cyclic AMP-dependent transcription factor ATF-6 beta

Gen-ID: 1388

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction