Actin, Alpha, gamma Antikörper (pTyr53, pTyr55)

Produktnummer ABIN7224640

Der Kaninchen Polyklonal anti-Actin, Alpha, gamma Antikörper (ABIN7224640) detektiert spezifisch Actin, Alpha, gamma in IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Actin, Alpha, gamma Antikörper (pTyr53, pTyr55) (ABIN7224640)

Target: Actin, Alpha, gamma

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Actin, Alpha, gamma Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Actin, Alpha, gamma Antikörper

Bindungsspezifität: pTyr53, pTyr55

Verwendungszweck: Rabbit Anti-Actin-α/γ (phospho Tyr55/53) Polyclonal Antibody

Spezifität: Phospho-Actin-α/γ (Y55/53) Polyclonal Antibody detects endogenous levels of Actin-α/γ protein only when phosphorylated at Y55/53.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Actin-alpha/gamma Phospho-Tyr55/53

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Actin, Alpha, gamma

Target: Actin, Alpha, gamma

Andere Bezeichnung: Actin-alpha/gamma

Hintergrund: ACTC1, ACTC, Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTG1, ACTB, ACTG, Actin, cytoplasmic 2, Gamma-actin, ACTG2, ACTA3, ACTL3, ACTSG, Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin,Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by ACTC1 (actin, alpha, cardiac muscle 1) belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in ACTC1 have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Gen-ID: 70, 71, 72

UniProt: P68032, P63261, P63267, P68133