AZI1 Antikörper (AA 280-360)

Produktnummer ABIN7213746

Der Kaninchen Polyklonal Anti-AZI1 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, AZI1 in Proben von Human zu detektieren.

Kurzübersicht für AZI1 Antikörper (AA 280-360) (ABIN7213746)

Target: AZI1 (5-Azacytidine Induced 1 (AZI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AZI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AZI1 Antikörper

Bindungsspezifität: AA 280-360

Verwendungszweck: AZI1 Polyclonal Antibody

Spezifität: AZI1 Polyclonal Antibody detects endogenous levels of AZI1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human AZI1 at AA range: 280-360

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu AZI1

Target: AZI1 (5-Azacytidine Induced 1 (AZI1))

Andere Bezeichnung: AZI1

Hintergrund: Rabbit Anti-AZI1 Polyclonal Antibody,AZI1, CEP131, KIAA1118, 5-azacytidine-induced protein 1, Centrosomal protein of 131 kDa, Cep131, Pre-acrosome localization protein 1,AZI1, also known as 5-azacytidine-induced protein 1, is a 1,083 amino acid protein that may play a role in spermatogenesis. AZI1 is most highly expressed in spinal cord, followed by testis, ovary, amygdala, cerebellum and thalamus. Low expression is present in other adult and fetal tissues and specific adult brain regions. AZl1 gene transcription begins in pachytene spermatocytes and expression of the gene is induced in cultivated fibroblasts on treatment with 5-azacytidine, which is known to lead to the demethylation of genomic DNA. The AZI1 gene is conserved in dog, cow, mouse, rat, chicken, and zebrafish, and exists as two alternatively spliced isoforms. AZI1 contains one IQ domain, and the gene that encodes it maps to human chromosome 17q25.3. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.,5-azacytidine-induced protein 1

Gen-ID: 22994

UniProt: Q9UPN4

Pathways: M Phase