TIMD4 Antikörper (AA 75-170)

Produktnummer ABIN715631

Der Kaninchen Polyklonal anti-TIMD4 Antikörper wird verwendet zum Nachweis von TIMD4 in Proben von Human. Er wurde validiert für WB, IHC (p), IHC (fro), IF (p) und IF (cc).

Kurzübersicht für TIMD4 Antikörper (AA 75-170) (ABIN715631)

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-TIMD4 Antikörper

Bindungsspezifität: AA 75-170

Verwendungszweck: TIM4 Polyclonal Antibody

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIM4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TIMD4

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Andere Bezeichnung: Tim4

Hintergrund:

Synonyms: SMUCKLER, Spleen, mucin-containing, knockout of lymphotoxin protein, T cell immunoglobulin and mucin domain containing protein 4, T-cell immunoglobulin and mucin domain containing 4, T-cell membrane protein 4, TIM-4, Tim4, Tim 4, TIMD 4.

Background: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. Studies have shown that TIM 4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM 1, and that this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM 4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM 4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM 1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

Gen-ID: 91937

Pathways: Cancer Immune Checkpoints