TIMD4 Antikörper (AA 75-170)

Produktnummer ABIN715631

Produktdetails anti-TIMD4 Antikörper

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Bindungsspezifität: AA 75-170

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIM4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TIMD4

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Andere Bezeichnung: Tim4 (TIMD4 Produkte)

Synonyme: RGD1564516 antikoerper, MGC99322 antikoerper, TIMD4 antikoerper, B430010N18Rik antikoerper, TIM-4 antikoerper, Tim4 antikoerper, SMUCKLER antikoerper, TIM4 antikoerper, T-cell immunoglobulin and mucin domain containing 4 antikoerper, T-cell immunoglobulin and mucin domain containing 4 L homeolog antikoerper, T cell immunoglobulin and mucin domain containing 4 antikoerper, Timd4 antikoerper, TIMD4 antikoerper, timd4.L antikoerper

Hintergrund:

Synonyms: SMUCKLER, Spleen, mucin-containing, knockout of lymphotoxin protein, T cell immunoglobulin and mucin domain containing protein 4, T-cell immunoglobulin and mucin domain containing 4, T-cell membrane protein 4, TIM-4, Tim4, Tim 4, TIMD 4.

Background: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. Studies have shown that TIM 4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM 1, and that this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM 4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM 4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM 1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

Gen-ID: 91937

Pathways: Cancer Immune Checkpoints