nectin-3 Antikörper (AA 431-549) (Cy7)
Kurzübersicht für nectin-3 Antikörper (AA 431-549) (Cy7) (ABIN715397)
Target
Alle nectin-3 (NECTIN3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 431-549
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Cow,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Nectin 3
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
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Andere Bezeichnung
- Nectin 3
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Hintergrund
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Synonyms: CD113, CDw113, DKFZP566B0846, FLJ90624, Nectin-3, Nectin3, Poliovirus receptor related 3, Poliovirus receptor related protein 3, Poliovirus receptor-related protein 3, PPR3, PRR3, PVRL 3, PVRL3, PVRL3_HUMAN, PVRR3.
Background: Nectins are immunoglobulin-like adhesion molecules that interact with afadin. Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin-catenin system in epithelial cells.The nectin/PRR-family consists of four members, nectin-1, -2, -3 and -4. All the members of the nectin family have two or three slice variants. Nectin 3 is mainly expressed in testis and placental tissues and interacts in vivo with both long and short isoforms of afadin.
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Gen-ID
- 25945
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Pathways
- Cell-Cell Junction Organization
Target
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