TSG101 Antikörper (AA 167-374)

Produktnummer ABIN7193932

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TSG101 in IHC, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TSG101 Antikörper (AA 167-374) (ABIN7193932)

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TSG101 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Klon: 8E10D10

Produktdetails anti-TSG101 Antikörper

Bindungsspezifität: AA 167-374

Verwendungszweck: TSG101 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human TSG101 (AA: 167-374) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu TSG101

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Andere Bezeichnung: TSG101

Hintergrund:

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

Molekulargewicht: 44 kDa

Gen-ID: 7251

UniProt: Q99816