Melanoma gp100 Antikörper (AA 25-192)

Produktnummer ABIN7193921

Der Maus Monoklonal Anti-Melanoma gp100-Antikörper wurde für FACS und ELISA validiert. Er ist geeignet, Melanoma gp100 in Proben von Human zu detektieren.

Kurzübersicht für Melanoma gp100 Antikörper (AA 25-192) (ABIN7193921)

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Melanoma gp100 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA

Klon: 5C6G8

Produktdetails anti-Melanoma gp100 Antikörper

Bindungsspezifität: AA 25-192

Verwendungszweck: PMEL Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PMEL (AA: 25-192) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Melanoma gp100

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Andere Bezeichnung: PMEL

Hintergrund:

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 70.2 kDa

UniProt: P40967