SIGLEC8 Antikörper (AA 17-216)
Kurzübersicht für SIGLEC8 Antikörper (AA 17-216) (ABIN7193804)
Target
Alle SIGLEC8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 17-216
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Verwendungszweck
- SIGLEC8 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human SIGLEC8 (AA: 17-216) expressed in E. Coli.
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Isotyp
- IgG2b
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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Andere Bezeichnung
- SIGLEC8
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Hintergrund
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Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983])
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Molekulargewicht
- 54 kDa
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Gen-ID
- 27181
Target
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