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SIGLEC8 Antikörper (Extracellular Domain)

SIGLEC8 Reaktivität: Human ELISA, IP, FACS Wirt: Maus Monoclonal 7C9 unconjugated
Produktnummer ABIN7013899
  • Target Alle SIGLEC8 Antikörper anzeigen
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    Reaktivität
    • 43
    • 7
    • 2
    Human
    Wirt
    • 33
    • 9
    • 1
    Maus
    Klonalität
    • 35
    • 8
    Monoklonal
    Konjugat
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIGLEC8 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 19
    • 19
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8, an eosinophil marker, expressed e.g. in lymph nodes and spleen.
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Immunogen
    Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1
    Klon
    7C9
    Isotyp
    IgG1
    Top Product
    Discover our top product SIGLEC8 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Andere Bezeichnung
    SIGLEC8 (SIGLEC8 Produkte)
    Synonyme
    SAF2 antikoerper, SIGLEC-8 antikoerper, SIGLEC8L antikoerper, SIGLEC8 antikoerper, sialic acid binding Ig like lectin 8 antikoerper, sialic acid-binding Ig-like lectin 8 antikoerper, SIGLEC8 antikoerper, LOC506364 antikoerper
    Hintergrund
    Sialic acid binding Ig like lectin 8,SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker, although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum, especially in case of eosinophil-associated diseases.,SAF2
    Gen-ID
    27181
    UniProt
    Q9NYZ4
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