SIGLEC8 Antikörper (Extracellular Domain)
Kurzübersicht für SIGLEC8 Antikörper (Extracellular Domain) (ABIN7013899)
Target
Alle SIGLEC8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- Extracellular Domain
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Verwendungszweck
- Anti-Hu SIGLEC8 Purified
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Produktmerkmale
- The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8, an eosinophil marker, expressed e.g. in lymph nodes and spleen.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Immunogen
- Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1
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Isotyp
- IgG1
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Applikationshinweise
- Flow cytometry: Recommended dilution: 1-4 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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Andere Bezeichnung
- SIGLEC8
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Hintergrund
- Sialic acid binding Ig like lectin 8,SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker, although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum, especially in case of eosinophil-associated diseases.,SAF2
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Gen-ID
- 27181
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UniProt
- Q9NYZ4
Target
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