KRT6A Antikörper (AA 253-352)

Produktnummer ABIN7193708

Der Maus Monoklonal Anti-KRT6A-Antikörper wurde für WB, ELISA, FACS und ICC validiert. Er ist geeignet, KRT6A in Proben von Human zu detektieren.

Kurzübersicht für KRT6A Antikörper (AA 253-352) (ABIN7193708)

Target: KRT6A (Keratin 6A (KRT6A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT6A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 7E3D1

Produktdetails anti-KRT6A Antikörper

Bindungsspezifität: AA 253-352

Verwendungszweck: KRT6A Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human KRT6A (AA: 253-352) expressed in E. Coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Andere Bezeichnung: KRT6A

Hintergrund:

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Molekulargewicht: 60 kDa

Gen-ID: 3853

UniProt: P02538