CDKN1C Antikörper

Produktnummer ABIN7193626

Dieser Maus Monoklonal Antikörper detektiert spezifisch CDKN1C in WB, ELISA, FACS, IHC und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CDKN1C Antikörper (ABIN7193626)

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDKN1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: 1F4A9

Produktdetails anti-CDKN1C Antikörper

Verwendungszweck: CDKN1C Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CDKN1C expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200-1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CDKN1C

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Andere Bezeichnung: CDKN1C

Hintergrund:

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

Molekulargewicht: 32.2 kDa

UniProt: P49918

Pathways: Zellzyklus, Dopaminergic Neurogenesis