S100B Antikörper (AA 1-92)

Produktnummer ABIN7193506

Dieses Maus Monoklonal-Antikörper erkennt spezifisch S100B in WB, FACS und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für S100B Antikörper (AA 1-92) (ABIN7193506)

Target: S100B (S100 Calcium Binding Protein B (S100B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Klon: 4C7H12

Produktdetails anti-S100B Antikörper

Bindungsspezifität: AA 1-92

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human S100B (AA: 1-92) expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu S100B

Target: S100B (S100 Calcium Binding Protein B (S100B))

Andere Bezeichnung: S100B

Hintergrund:

Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Aliases: NEF, S100, S100-B, S100beta

Molekulargewicht: 10.7 kDa

Gen-ID: 6285

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine