NOXA Antikörper (AA 1-54)
Kurzübersicht für NOXA Antikörper (AA 1-54) (ABIN7193484)
Target
Alle NOXA (PMAIP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-54
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Verwendungszweck
- PMAIP1 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human PMAIP1 (AA: 1-54) expressed in E. Coli.
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Isotyp
- IgG1
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anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-54) antibody
PMAIP1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) antibodyPMAIP1 Reaktivität: Human ELISA, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibodyPMAIP1 Reaktivität: Human WB, IF, IHC, FACS Wirt: Maus Monoclonal 114C307-1 unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (Internal Region) antibodyVerified PMAIP1 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) antibodyPMAIP1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (N-Term) antibodyPMAIP1 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
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Andere Bezeichnung
- PMAIP1
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Hintergrund
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The protein encoded by this gene promotes activation of caspases and apoptosis, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
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Molekulargewicht
- 6 kDa
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Gen-ID
- 5366
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UniProt
- Q13794
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Pathways
- p53 Signalweg, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
Target
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