Mesothelin Antikörper (AA 37-286)

Produktnummer ABIN7193454

Dieses Anti-Mesothelin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Mesothelin in ELISA und FACS. Geeignet für Human.

Kurzübersicht für Mesothelin Antikörper (AA 37-286) (ABIN7193454)

Target: Mesothelin (MSLN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Mesothelin Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: 4H12F8

Produktdetails anti-Mesothelin Antikörper

Bindungsspezifität: AA 37-286

Verwendungszweck: MSLN Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MSLN (AA: 37-286) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Mesothelin

Target: Mesothelin (MSLN)

Andere Bezeichnung: MSLN

Hintergrund:

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molekulargewicht: 69 kDa

UniProt: Q13421

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process