Rubicon Antikörper (AA 859-972)
Kurzübersicht für Rubicon Antikörper (AA 859-972) (ABIN7193445)
Target
Alle Rubicon (KIAA0226) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 859-972
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Verwendungszweck
- RUBCN Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human RUBCN (AA: 859-972) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Rubicon (KIAA0226) (KIAA0226)
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Andere Bezeichnung
- RUBCN
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Hintergrund
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The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Molekulargewicht
- 108.6 kDa
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Gen-ID
- 9711
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UniProt
- Q92622
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Pathways
- Autophagie
Target
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