SETD2 Antikörper (AA 2054-2245)

Produktnummer ABIN7193416

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SETD2 in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SETD2 Antikörper (AA 2054-2245) (ABIN7193416)

Target: SETD2 (SET Domain Containing 2 (SETD2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SETD2 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: 4G11E6

Produktdetails anti-SETD2 Antikörper

Bindungsspezifität: AA 2054-2245

Verwendungszweck: SETD2 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human SETD2 (AA: 2054-2245) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Andere Bezeichnung: SETD2

Hintergrund:

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]

Molekulargewicht: 287.6 kDa

Pathways: Tube Formation