KDM2A Antikörper (AA 1-150)

Produktnummer ABIN7193407

Dieses Maus Monoklonal-Antikörper erkennt spezifisch KDM2A in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KDM2A Antikörper (AA 1-150) (ABIN7193407)

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KDM2A Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 5C11F7

Produktdetails anti-KDM2A Antikörper

Bindungsspezifität: AA 1-150

Verwendungszweck: KDM2A Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human KDM2A (AA: 1-150) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu KDM2A

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Andere Bezeichnung: KDM2A

Hintergrund:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Molekulargewicht: 132.8 kDa

Gen-ID: 22992

UniProt: Q9Y2K7

Pathways: Warburg Effekt