PIDD Antikörper (AA 776-910)

Produktnummer ABIN7193396

Der Maus Monoklonal Anti-PIDD-Antikörper wurde für ELISA validiert. Er ist geeignet, PIDD in Proben von Human zu detektieren.

Kurzübersicht für PIDD Antikörper (AA 776-910) (ABIN7193396)

Target: PIDD (P53-Induced Death Domain Protein (PIDD))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PIDD Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 3C5G8

Produktdetails anti-PIDD Antikörper

Bindungsspezifität: AA 776-910

Verwendungszweck: PIDD1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu PIDD

Target: PIDD (P53-Induced Death Domain Protein (PIDD))

Andere Bezeichnung: PIDD1

Hintergrund:

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Molekulargewicht: 99.7 kDa

Gen-ID: 55367

UniProt: Q9HB75

Pathways: p53 Signalweg, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity