CD27 Antikörper (AA 20-144)
Kurzübersicht für CD27 Antikörper (AA 20-144) (ABIN7193332)
Target
Alle CD27 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 20-144
-
Verwendungszweck
- CD27 Antibody
-
Aufreinigung
- Purified antibody
-
Immunogen
- Purified recombinant fragment of human CD27 (AA: 20-144) expressed in E. Coli.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- CD27 (CD27 Molecule (CD27))
-
Andere Bezeichnung
- CD27
-
Hintergrund
-
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
-
Molekulargewicht
- 29.1 kDa
-
Gen-ID
- 939
-
UniProt
- P26842
-
Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
-