ITGA4 Antikörper (AA 833-977)
Kurzübersicht für ITGA4 Antikörper (AA 833-977) (ABIN7193242)
Target
Alle ITGA4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 833-977
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Verwendungszweck
- CD49D Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CD49D (AA: 833-977) expressed in E. Coli.
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Isotyp
- IgG2a
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- ITGA4 (Integrin alpha 4 (ITGA4))
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Andere Bezeichnung
- CD49D
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Hintergrund
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The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
- 114.9 kDa
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Gen-ID
- 3676
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UniProt
- P13612
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Pathways
- Integrin Complex
Target
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